ANAESTHESIOLOGY - GENERAL ANAESTHESIA / LETTER TO EDITOR
Opioid-free versus opioid-sparing anaesthesia: is regional anaesthesia the variable that matters?
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Department of Emergency Medicine, St. Vincent’s University Hospital, Dublin, Ireland
 
 
Submission date: 2026-09-18
 
 
Acceptance date: 2026-10-25
 
 
Publication date: 2026-11-04
 
 
Corresponding author
James Lardner   

Department of Emergency Medicine, St. Vincent’s University Hospital, Elm Park Dublin 4, D04 County Dublin, Ireland
 
 
Anaesthesiol Intensive Ther 2026;58(1):226
 
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REFERENCES (4)
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Danel JK, Copik MM, Zdanowski S, Reysner M, Smyła-Gruca W, Białka S. Opioid-sparing and opioid-free anaesthesia: concepts, rationale, evidence, and practical implications. Anaesthesiol Intensive Ther 2026; 58: 179-188. DOI: 10.5114/ait/226446.
 
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Mistry T, Nair AS. Opioid-free anaesthesia: a meta-analytic mirage or a methodological misstep? J Anesth Analg Crit Care 2025; 5: 69. DOI: 10.1186/s44158-025-00300-8.
 
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de Carvalho CC, El-Boghdadly K, Guedes IHL, Dantas MVM, Tomé DPB, Ramoset IB, al. Opioid-free vs. opioid-inclusive anaesthesia with or without regional anaesthesia for postoperative pain: a systematic review with network meta-analysis of randomised controlled trials. Anaesthesia 2026; 81: 702-712. DOI: 10.1111/anae.70121.
 
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Gricourt Y, Cuvillon P, Forget P. Opioid-free anaesthesia as a valuable alternative to opioid-based practices: evidence and future challenges. Pain Manag 2025; 15: 721-731. DOI: 10.1080/17581869.2025.2542719.
 
eISSN:1731-2531
ISSN:1642-5758
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